Bacitraciniscomprisedofnumerousantimicrobialpeptidefractions.NotablefractionsincludeA,A1,B,B1,B2,C,D,E,F,G,andX.Standardgradebacitracin(B002)isamixtureofthesefractions.BacitracinAisthemostactiveandpotentpeptidefractioninbacitracinandisverysimilartoitsbacitracinBcounterpart.

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CASNumber

N/A

MolecularFormula

C₆₅H₁₀₁N₁₇O₁₆S

MolecularWeight

1408.69g/mol

MechanismofAction

Bacitracinpreventsphosphorylationofbactoprenol;atransportproteinwhichcarriespeptidoglycancomponentsoutsidethecellmembrane.Withouttheactivephosphorylatedbactoprenol,peptidoglycansynthesiscannotbecompleteandthecelllyses.Twomechanismsofbacitracinresistanceareunderstood.OnemechanismreliesonaproteincalledaBcrABCtransporterwhichpumpsbacitracinoutafterithasenteredthecell.AnalternativemechanismisduetoanotherproteincalledBacAwhichprovidestheactivephosphorylatedbactoprenolfromadifferentsyntheticpathway.

StorageConditions

-20°C

TariffCode

2941.90.5000

Spectrum

BacitracinprimarilytargetsthecellwallinmembersofthegrampositivebacteriaincludingStreptococcuspyogenesandStaphylococcusaureus.

Specifications:

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